Employer : Children's Cancer Institute
Closing date: 20/05/2026
Brief position description:
For over 40 years, our shared commitment to curing childhood cancer has united us. Together, we continue to accelerate the answers to make that possible.
The ZERO Senior Clinical Bioinformatician coordinates the clinical accreditation and maintenance of ZERO's multi-omic precision medicine testing platform, by ensuring bioinformatics pipelines meet ISO 15189 and NATA standards. Working collaboratively with researchers, scientists, precision oncology specialists, clinicians, pathologists, sequencing service providers, and quality teams across Children's Cancer Institute, Kids Cancer Centre, and nine national trial sites, this role provides technical expertise for the transition of established research-grade genomic workflows into clinically accredited diagnostic services.
This role is responsible for validation and ongoing quality assurance of bioinformatics pipelines processing germline and somatic whole genome sequencing, transcriptome, methylation, and other omic data. The ZERO Senior Clinical Bioinformatician will maintain computational frameworks for analytical validation, monitor quality control systems, maintain regulatory documentation, and ensure reproducibility and traceability of all bioinformatics workflows. This includes preparing NPAACcompliant validation reports, implementing version control systems, and taking part in competency frameworks for bioinformatics staff.
The ZERO Senior Clinical Bioinformatician plays an important role in achieving NATA accreditation readiness, ensuring computational processes integrate seamlessly with laboratory quality management systems and clinical reporting workflows. This position requires the ability to understand and work with bespoke platforms whilst implementing best practices for ISO 15189- accredited environments.
To succeed you will have...
- Postgraduate qualification in Bioinformatics, Computational Biology, or a closely related field.
- Minimum 5 years of experience in bioinformatics, with at least 3 years in a clinical setting.
- Good understanding of regulatory and clinical standards for accrediting molecular assays under ISO 15189, NPAAC, NATA.
- Familiarity with LIMS, electronic health/medical records (EMR), and clinical reporting systems.
- Familiarity with HL7 FHIR / GA4GH standards.
- Expertise in multi-omic data analysis and integration.
- High-performance computing and cloud infrastructure knowledge.
- Deep expertise in programming languages such as Python, R, or equivalent.
- Strong understanding of bioinformatics tools and databases.
- Experience with clinical-grade software development and version control systems.
- Excellent written and verbal communication skills.
- Excellent problem-solving skills and attention to detail.
- Strong communication and teamwork capabilities.
We will support you to be your best with benefits that include but are not limited to:
- Working in a world-class, purpose-built facility, Australia’s only centre solely dedicated to curing childhood cancer where researchers, clinicians and patients are all brought together in one location.
- Focus on employee wellbeing, including up to 5 gifted wellbeing days off (paid) per year
- Access to Fitness Passport, with access to an extensive choice of fitness facilities across Sydney at discounted rates
- Corporate discounts and discounts on education through UNSW
Join us to shape a future every child deserves and to find meaning in your own. Because together, we can cure every child of cancer. It’s not if, it’s when.
Job website: http://ccia.connxcareers.com/Job/Details/f669e68c8b7f41d0a6d8b5f6ac741be9
Contact name: Roxane Legaie
Contact email: rlegaie@ccia.org.au