Computational Mathematician / Bioinformatician (C++)

Employer: Children's Medical Research Institute

Closing date: 4th April 2018

Brief position description: Children's Medical Research Institute (CMRI) is seeking an experienced computational mathematician to help us deploy a data processing and analytics pipeline for clinical cancer proteomics. The successful candidate will be passionate about bringing to bear their experience on challenging problems that have tangible benefit to patient wellbeing. 

One of CMRI’s flagship projects, ProCan, is an exciting international initiative that is building a proteomics database for all types of cancer – in children and adults – to increase the accuracy of cancer treatment decisions for each individual patient. Equipped with six SCIEX mass spectrometers and local high-performance computing (700TB / 480 cores), ProCan processes tumour samples through a proteomic method, SWATH-MS, that allows fast mass spectrometric conversion of small amounts of tissue (biopsy level) into a single, permanent digital file representing the quantitative proteome of the sample. ProCan will analyze approximately 70,000 individual cancer samples over the next 5-7 years, and a major outcome of the initiative will be the creation of a high-availability database and data visualization system which can be used for discovery research, and by clinicians to inform their treatment decisions.

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Contact name: Paulina Baranowski

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