Employer: Baker Heart and Diabetes Institute

Closing date: 8 April 2024

Brief position description: This postdoctoral post is a collaborative project with the Epigenetics in Human Health and Disease Team. This work focuses on characterizing the functional roles of regulatory proteins critical in gene transcription and examine the link to human disease using genetic, epigenomic and molecular approaches. The program is interested in understanding the transcriptional components in the regulation of metabolic memory and cardiac disease and further extend our understanding epigenetics in pre-clinical studies with a focus on cohort populations. This research will potentially provide tools for novel therapies. These key areas of therapeutic interest emphasising human studies have led to publications of high impact and international recognition.

This program is focused on the epigenetic analyses of prominent international cohorts. We have collected patient material to assess epigenomic indices using ChIP-seq, RNA-seq and Methyl-seq. The project aims to characterize the epigenetic landscape with the progression and development of disease. The aim of the work is to bridge the clinical and preclinical research in our department.

Job website: http://www.seek.com.au/job/74186574

Contact name: Sam El-Osta

Contact email: sam.el-osta@baker.edu.au