Employer: Peter MacCallum Cancer Centre
Closing date: 8 March 2024
Brief position description: Applications are invited to join an exciting multi-discliplinary research program within Mark Dawson’s Laboratory (https://smex-ctp.trendmicro.com:443/wis/clicktime/v1/query?url=www.thedawsonlab.com&umid=de34786c-b3ea-4c7d-b51b-dcb7d64b3414&auth=4d41e25c5d761d3d9b3f3fb6ac781e525dd700b4-bb19eb3663de449407d29df43edfe9515cc2e7cc) at the Peter MacCallum Cancer Centre. The research will explore the molecular mechanisms of clonal dominance in normal development and in cancer biology to provide insights into cell fate decisions, normal and malignant stem cell renewal, treatment response and resistance in cancer.
The position will involve the analysis of large-scale single cell data through the application of best-practice bioinformatics workflows and the development of innovative methods as required. The position will require a highly motivated bioinformatician or computational biologist to provide support for a variety of projects that build on innovative methods including SPLINTR (Fennell, Vassiliadis et al; Nature 2022, Holze et al BioRxiv 2023) – a cellular barcoding and lineage tracing technique. The role will include the analysis of a range of next generation sequencing data, including scRNA-seq, scChIP-seq, scATAC-seq and spatial transcriptomics. The role will require proficiency in at least one relevant programming language (e.g. R/Python/Perl) and experience working on a high-performance computing cluster. The individual will collaborate very closely with other bioinformaticians, cancer cell and molecular biologists in the Dawson laboratory team to work on joint initiatives.
The position will be in a research environment that includes a large and interactive group of bioinformaticians and computational biologists in the Computational Cancer Biology Program and the Bioinformatics Core Facility. The position will be initially for a fixed term of 12 months with the opportunity to extend for up to 5 years. Remuneration will be commensurate with qualifications and experience.
Applicants to this role should provide a covering letter outlining relative key skills and experience to assist us with our assessment.
Alternatively, please contact us using the information below for a confidential discussion.
Hiring Manager: Dane Vassiliadis and Enid Lam
Email: Dane.Vassiliadis@petermac.org and Enid.Lam@petermac.org
Contact name: Enid Lam
Contact email: enid.lam@petermac.org