Bioinformatician @ Sydney

Employer: Garvan Institute of Medical Research

Closing date: 28-11-2019

Brief position description: The Garvan Institute of Medical Research (Garvan) is one of Australia’s leading medical research institutes, with over 600 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses genomics and epigenetics, cancer, immunology, bone biology, neuroscience, and diabetes and metabolism. These research activities are organised within four themes: Genomics, Cancer, Inflammatory Diseases, and Healthy Aging, and two Centres: the Kinghorn Centre for Clinical Genomics and the Garvan-Weizmann Centre for Cellular Genomics.

The Human Comparative and Prostate Cancer Genomics (HCPCG) Laboratory is focused on understanding the complexities of the human and cancer genome and how genomic variation has shaped human diversity, health, cancer evolution, risk and outcome.

This is a newly funded position, from the Australian National Health and Medical Research Council (NHMRC), to examine genomic alterations contributing to both ethnic disparities and those driving aggressive prostate cancer. The project is prefaced on the hypothesis that somatic (acquired) genomic alterations are fundamental drivers of clinical heterogeneity and treatment response in prostate cancer. Thus, the project seeks to identify the somatic genomic landscape as potential biomarkers of disease and treatment outcome by using whole-genome sequencing of tumour and matched normal patient samples.

The Opportunity
Reporting to the Head of HCPCG, the Bioinformatics Research Officer will focus on the implementation of high-throughput computational tools to analyse next-generation sequencing (NGS) data to identify somatic variations associated with prostate cancer.

This is a one year full time opportunity in the first instance with the possibility to extend.

Key Responsibilities
Perform computational and statistical analyses of whole genome sequencing data
Implement existing bioinformatics tools necessary for large-scale population-level genome analysis
Manage movement and storage of genomic data related to the project
Ensure appropriate written documentation of work
Work independently and as part of a team
Support writing of manuscripts related to the project
Other duties relevant to the role

About You
Postgraduate Degree in a relevant field (e.g. bioinformatics, cancer genomics, or comparative genomics) or Bachelors’ Degree with demonstrated experiences in these fields
Experience with bioinformatics or computational analyses, particularly for NGS data
Familiarity of NGS technologies, particularly of the Illumina platform
Experience with installing and implementing existing bioinformatics software
Familiarity with the commandline and use of HPC resource

How to Apply
All applications must include:
A cover letter
Your resume including at least 2 referees
Copies of relevant qualifications / academic transcripts

Closing Date
The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.

Job website:

Contact name: Shree Chattopadhyay

Contact email: