Bioinformatician (Software Engineer) @ SA

Position title: Bioinformatician (Software Engineer)

Employer: SAGC/SAHMRI

Closing date: 30th September 2023

Brief position description: About SAGC

The South Australian Genomics Centre (SAGC) is a multi-institutional, national genomics and bioinformatics facility that is supported by Bioplatforms Australia (BPA) through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS). The SAGC has consolidated genomics and bioinformatics expertise in the state, with a group of ~12 genomics and bioinformatics staff working side-by-side to deliver innovative genomics and bioinformatics solutions across all areas of genomics research, including agriculture, healthcare and ecology.

About the Position
Full-time, 2 year contract
Salary range: 80,000 - 95,000 AUD

About the Role
Key responsibilities include:
* Develop reproducible analytical workflows with a view to improve internal efficiencies as well as client experiences
* Provide end-to-end bioinformatics analysis support to SAGC 
* Contribute to/or lead the drafting of reports and publications

Job website: https://sahmri.org.au/careers-and-study/working-at-sahmri/vacancies/bioinformatician-software-engineer

Contact name: Sen Wang

Contact email: Sen.Wang@sahmri.com

Bioinformatics Research Assistant @ NSW

Position title: Bioinformatics Research Assistant

Employer: Garvan Institute of Medical Research

Closing date: 6/9/23

Brief position description: The Garvan Institute of Medical Research brings together world-leading clinicians and basic and translational researchers to break down barriers between traditional scientific disciplines and find solutions to disease. 

The Swarbrick lab are global leaders in the application of cellular genomics to human cancer, to find new diagnostics and treatments for society’s most challenging cancers. We are a diverse multidisciplinary team of scientists and clinicians with a vision to change cancer medicine. More information can be found at https://www.swarbricklab.com/


THE OPPORTUNITY 
The Research Assistant is accountable for assisting with bioinformatic analysis of experiments conducted within the Swarbrick Laboratory, with strategic guidance and training from postdoctoral bioinformaticians in the Swarbrick Laboratory. 

Major projects include generation of an international, large-scale, multi-omic breast cancer atlas and understanding the cellular mediators of response to cancer immunotherapy in breast cancer and melanoma. The Laboratory is generating substantial single-cell sequencing (scRNA-Seq), spatial transcriptomics and other genomic and proteomic datasets from clinical samples and preclinical models. 

This role will suit a computational science/bioinformatics graduate with training and experience in advanced computational techniques and with an interest in cancer biology, spatial biology or cellular genomics. 

Salary: $79,500 + 14% super + salary packaging 
Employment Type: 2 year term contract 

SNAPSHOT OF BENEFITS 
Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom) 
Ample opportunities for on-going training and development 
Stimulating, diverse and highly international research environment 
Flexible work arrangements e.g. start / finish times etc 
18 weeks paid parental leave for both parents including paid superannuation 
A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave 
Discounted Health Insurance 
Lifestyle discounts with our community partners 

WHAT YOU WILL DO 
Key responsibilities include: 
Developing, maintaining and executing bioinformatic pipelines/workflows, particularly in relation to scRNA-seq and spatial transcriptomic data 
Contribute to the existing codebase in collaboration with other team members, including debugging, refactoring and enhancing legacy code 
Document new code, and make improvements to existing documentation 
Track, archive and actively manage raw and processed data in accordance with established procedures and policies 
Analyse clinical and experimental data, with an emphasis on relevance to clinical translation 
Assist other team members with their analyses 
Adopt, test and benchmark analytical packages for incorporation into analyses and standardised pipelines 
Present results internally and externally 

ABOUT YOU 
The position would suit a graduate from a quantitative discipline (bioinformatics, statistics, mathematics, physics, software engineering, information technology, computer science or a related field) 
Experience with version control systems, particularly git 
Experience with R and/or Python 
Experience with workflow control frameworks, such as Snakemake and/or Nextflow 
Familiarity with the Unix command line and high-performance computing environments and/or cloud computing 
Knowledge of the fundamentals of molecular biology: DNA transcription and translation 
Skills in analysis of large molecular datasets, such as WGS, RNA-seq, ChIP-seq, etc. Experience with scRNA-seq and spatial technologies such as Visium or Xenium would be particularly beneficial 
Strong commitment to data organisation and implementation of quality controls 
Excellent communication skills for written reports and oral presentations 
Desire to work co-operatively with other team members 

ABOUT GARVAN 
The Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia’s largest and most highly regarded MRI’s. 

Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome. 

We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease. 

Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture ‘add’, not culture ‘fit’ and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively. 

HOW TO APPLY 
To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. Only applicants with full working rights in Australia are eligible to apply for this role.

Job website: http://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/details/Computational-Research-Assistant---Cancer_PRF6893-1

If you have issues opening the link, please email the talent team at Garvan: talent@garvan.org.au

Contact name: Iana Ramos

Contact email: i.ramos@garvan.org.au

Bioinformatician @ NSW

POSITION TITLE: Bioinformatician

EMPLOYER: NSW Health Pathology

CLOSING DATE: 13 August 2023 - 11:59pm

BRIEF POSITION DESCRIPTION:

*Employment Type*: Full Time, 1 year
*Position Classification*: Health Manager Level 2
*Remuneration*: $102,640 - $121,739 per annum plus superannuation
*Hours Per Week*: 38
*Requisition ID*: REQ411944
*Location*: Sydney or Newcastle (flexible)

This position offers an exciting opportunity to support the implementation of a bioinformatics workflow for cancer genomic testing at NSW Health Pathology's State-Wide Genomics Service. You will work in a team of highly trained and experienced bioinformaticians, scientific staff, and DevOps engineers that offer innovative genomic testing solutions. This position is responsible for the the development, validation, and testing of an accredited bioinformatic pipeline for comprehensive genome profiling, as well as the integration of this pipeline into existing health systems at NSWHP. 

Position description: https://ocxz.cit.health.nsw.gov.au/excluded-apps/XXRecRequisitionPD-context-root/faces/XXRecRequisitionPDPG?xxJobId=REQ422254

JOB WEBSITE: http://jobs.health.nsw.gov.au/jobs/bioinformatician-216955

CONTACT NAME: Eva Chan

CONTACT EMAIL: eva.chan@health.nsw.gov.au

TRAIL Research Bioinformatician - Genomics @ NSW

POSITION TITLE: TRAIL Research Bioinformatician - Genomics

EMPLOYER: The Sydney Children's Hospitals Network

CLOSING DATE: 11/08/2023 - 11:59 PM

BRIEF POSITION DESCRIPTION:

Employment Type: Temporary Full Time up to 31/08/2027
Position Classification: Health Mgr Lvl 2
Remuneration: 102640 - 121739 full time equivalent base salary range (excludes super, leave loading and salary packaging)
Hours Per Week: 38
Requisition ID: REQ420864

Sydney Children's Hospitals Network (SCHN) is seeking a Bioinformatician or Computational Biologist to join the Clinical Team fulltime at Sydney Children's Hospitals Network. The ideal candidate has practical experience in bioinformatics as well as statistics and advanced programming abilities. 

This role will join a high-performing team, embedded across NSW Health Pathology (NSWHP) and SCHN. This role will also enable close collaboration with the CSIRO, and Australian Genomics initiatives in Queensland, Victoria, NSW and South Australia.

** Background ** 
In 2022 the Australian Government committed to increase equity of access and consistency and expand the number of conditions screened through existing newborn bloodspot screening (NBS) programs. In Australia, these programs are managed and delivered along jurisdictional lines by State Health Departments under a federated health model.

Equally in 2022, the Genomics Health Futures Mission (GHFM) and the National Health and Medical Research Council (NHMRC) awarded more than AUD$15 million to support 5 research programs, which are exploring the application of first-tier and second-tier genomic NBS as well as health economic, ethics and equity considerations. 

The Newborn GEN SEQ TRAIL (aka the TRAIL study) is one of these 5 studies, looking to implement genomic NBS in NSW, led by Clinical Professor Bruce Bennetts.

** The Role ** 
The successful candidate will play a significant role in delivering new and existing projects in collaboration with NSWHP ICT and local clinical laboratory services. Reporting to the Senior Bioinformatician, this position is responsible for the efficient and effective delivery of defined project outcomes within agreed timeframes, budgets, quality, and resources.

Specific contributions will include the MRFF funded NEWBORN GEN SEQ TRAIL study. This role will support the development of a bioinformatics pipeline associated with the potential of offering genomic Newborn Bloodspot Screening (NBS) to parents of newborn babies across NSW. 

Please visit https://iworkfor.nsw.gov.au/job/trail-research-bioinformatician-genomics-419204 for more details and see https://ocxz.cit.health.nsw.gov.au/excluded-apps/XXRecRequisitionPD-context-root/faces/XXRecRequisitionPDPG?xxJobId=REQ420864 for the position description.

JOB WEBSITE: http://iworkfor.nsw.gov.au/job/trail-research-bioinformatician-genomics-419204

CONTACT NAME: Eva Chan

CONTACT EMAIL: eva.chan@health.nsw.gov.au

Research Fellow in Multiomics, AI and Machine Learning @ VIC

POSITION TITLE: Research Fellow in Multiomics, AI and Machine Learning

EMPLOYER: WEHI

CLOSING DATE: 23 August 2023

BRIEF POSITION DESCRIPTION:

An opportunity exists for a talented and motivated computational scientist to join an exciting new program developing and applying artificial intelligence and machine learning methods to analyze biomedical molecular data at Australia's pre-eminent biomedical research institute.

About the Position
Recognizing the emerging importance of artificial intelligence and machine learning in biomedical research, WEHI is investing strongly in a new research program and is creating multiple new AI Research Fellow positions.

This position will be based in the Papenfuss Laboratory within the Computational Biology Theme. It will involve developing and applying machine learning techniques to integrate large-scale multi-omics data to identify disease subtypes and predictive biomarkers in a variety of health-related settings, including infectious disease and cancer. Projects will involve large-scale single cell or spatial omics, imaging, genome and/or other omics data. There will be opportunity for methods development.

The successful candidate will join an interactive team of computational scientists in a supportive and flexible working environment. They will work alongside other AI and machine learning experts as part of a broader AI research community developing at WEHI. The research is well-supported by state-of-the-art computing facilities and engineering expertise.

The successful candidate will have a PhD in a quantitative discipline such as Computer Science, Bioinformatics, Computational Biology, Mathematics, Statistics or Physics, together with expertise in machine learning techniques applied to multi-omics data.

Selection Criteria
Personal Qualities:
A PhD in Bioinformatics, Computational Biology, Computer Science, Mathematics, Statistics or Physics demonstrated through publications or a thesis
A collegiate approach and interest in collaboration
Good time management skills
Excellent skills engaging with and managing collaborators and stakeholders
Essential Knowledge and Skills:
Expertise in machine learning, artificial intelligence and multiomics
Experience with genomic, transcriptomic or other high-throughput data
Experience applying machine learning techniques to biological data
High-level data management skills
Highly developed written and verbal communication skills
Terms of Appointment
This full-time position is for a period of 3 years in the first instance, with possible extension dependent on performance. Salary Scale will be from Research Officer (RO) A6 to Senior Research Officer (SRO) B1 between $97,152 - $109,778. Salary will be dependent on the candidate’s experience.

Up to 17% superannuation and very attractive salary packaging options are available. Salary will be dependent on the candidate’s experience.

JOB WEBSITE: https://wehi.wd3.myworkdayjobs.com/WEHI/job/Parkville-Victoria-Australia/Research-Officer-Senior-Research-Officer-in-Multi-omics-Integration---Biomarker-Discovery_JR2084-1

CONTACT NAME: Tony Papenfuss

CONTACT EMAIL: papenfuss@wehi.edu.au

Research Officer/Research Assistant @ QLD

POSITION TITLE: Research Officer/Research Assistant

EMPLOYER: QIMR Berghofer Medical Research Institute

CLOSING DATE: 21 August 2023

BRIEF POSITION DESCRIPTION:

Applications are invited for an enthusiastic and highly-motivated bioinformatician to join the Cancer Genetic Susceptibility Laboratory. This position is to work on the study of gynaecological cancer genetics, using functional genomic datasets.

We are seeking someone with strong statistical and computational skills who is interested in working with GWAS and large scale functional genomic datasets to perform integrative analyses and identify target genes. We are looking for someone with experience in analysis of functional genomics assays, such as CRISPR screens, RNA-seq, ATAC-seq and global chromatin conformation capture data (e.g. HiChIP). The successful applicant would be provided opportunity for dissemination of research findings (e.g. meetings and conferences) and for publication of research articles.

JOB WEBSITE: http://www.seek.com.au/job/68857920?type=standout#sol=28b665e8495a65ad3bdb216e849190d1fe4d342f

CONTACT NAME: Tracy O'Mara

CONTACT EMAIL: tracy.omara@qimrberghofer.edu.au

CSIRO Postdoctoral Fellowship in Anti-viral Immuno-engineering Bioinformatics

Position title: CSIRO Postdoctoral Fellowship in Anti-viral Immuno-engineering Bioinformatics

Employer: CSIRO

Closing date: 11 August

Brief position description: CERC Fellows are appointed for three years or full time equivalent. 
The CERC Fellow will play a critical role in an overarching project which involves a multi-disciplinary, multi-CERC Fellow team to develop and validate a novel solution to address viral outbreaks in livestock and aquaculture species, leveraging new developments in the field of gene editing. The overarching project brings together a multi-disciplinary team to address this challenge which cost the agricultural industry millions of dollars every year. Harnessing the collective expertise across the fields of immunology, genome engineering and bioinformatics, the multi-CERC Fellow team will draw on the SynBio principle of “Design-Build-Test-Learn” to adapt and optimize a key antiviral mechanism from bacteria. The adapted antiviral platform can then be transplanted into agricultural species to enhance resilience to viral pathogens.
The CERC Fellow will develop models of viral evolution and use this to inform the design of CRISPR/Cas13 based antivirals for applications in livestock and aquaculture industries. Specifically, they will use machine learning to approaches to understand how viruses evolve in response to selection pressure to better understanding escape pathways and use this to design CRISPR/Cas13 anti-viral that are robust to escape mutations. The Fellow will work closely with multidisciplinary experts in aquaculture, livestock, virology and genome engineering to achieve project outcomes. The project also aligns to the Immune Resilience Future Science Platform (FSP) which aims to harness the fundamental understanding of the immune system to develop novel strategies and platforms that will build resilience in animals to combat disease and parasite challenges.
This role is part of a “Team Sport” CERC Fellowship where three CERC Fellows work with multiple teams collaborating on an overarching, multi-disciplinary research project. Each CERC Fellow will lead an individual sub-project, contributing their expertise, and work closely with the other team members with the aim of delivering significant scientific and translational impact on a broad research topic.

Job website: http://jobs.csiro.au/job-invite/93532/

Contact name: Laurence Wilson

Contact email: laurence.wilson@csiro.au

Research Officer, Bioinformation @ VIC

Position title: Research Officer, Bioinformation

Employer: University of Melbourne

Closing date: 04 Aug 2023

Brief position description: This is an exciting opportunity for a highly motivated Research Officer to join the research group of Professor Lachlan Coin at The Peter Doherty Institute for Immunity and Infection. As part of the NHMRC-funded project NITRIC, you will have the unique opportunity to contribute to the largest pediatric cardiac surgical intervention trial worldwide. By implementing cutting-edge genomic analyses and machine learning approaches, you will play a crucial role in identifying gene expression patterns associated with patient outcomes in congenital heart disease. Join our collaborative team and make a significant impact in the field of computational biology and bioinformatics, while developing your own independent program of research and contributing to leading specialist journals.

Job website: http://jobs.unimelb.edu.au/en/job/913455/research-officer-bioinformation

Contact name: Lachlan Coin

Contact email: lachlan.coin@unimelb.edu.au

Domain Bioinformatician (Research Officer) @ VIC

Position title: Domain Bioinformatician (Research Officer)

Employer: Baker Heart and Diabetes Institute

Closing date: 15/07/2023

Brief position description: This is a position for a Research Officer eager to provide their biostatistics expertise for experimental and study design, data analyses and interpretation at the Institute, and perform high quality research in bioinformatics, genomics or computational biology. Half of the effort will be supporting other labs in Baker, and the other half will be independent research. Since many collaborations involve biobank data analysis, a basic understanding of epidemiology is desirable. We are particularly interested in candidates with experience and a strong interest in single-cell analysis.

Job website: http://www.seek.com.au/job/68128798

Contact name: Fumihiko Takeuchi

Contact email: Fumihiko.Takeuchi@baker.edu.au

Bioinformatics Research Officer / Senior Research Officer @ VIC

Position title: Bioinformatics Research Officer / Senior Research Officer

Employer: WEHI

Closing date: 07/07/2023

Brief position description: An excellent opportunity is available for a Bioinformatics Research Officer / Senior Research Officer to work on spatial omics as part of the Advanced Technology and Biology Division and Bioinformatics Division (Phipson Lab) at Australia’s pre-eminent biomedical research institute. 

WEHI is building on its reputation for excellence in advanced technologies with the development of a nationally leading centre for spatial omics and the acquisition of multiple new technologies in a highly collaborative and open framework. 
In conjunction with the Bioinformatics Division and many scientific collaborators, the Advanced Genomics Facility at WEHI comes to grips with data from many cutting-edge technologies, and ground-breaking projects, every day. 
In this role, you will share in the analysis of data from experiments in single-cell and spatial omics, applying rigorous principles and using the latest computational and statistical approaches. 
You will combine contributions to many diverse projects, taking on experimental design, trouble-shooting and data evaluation in a close partnership with our laboratory team, with a more prominent role in developing methodologies or the detailed analysis of selected key projects. 
The role is pivotal in building closer links between technology and analytical streams at WEHI and designed to suit someone keen to work in one of the most dynamic areas of bioscience, looking either to build on a recent PhD by gaining a lot of experience quickly (RO) or who has substantial existing experience in computational data analysis but may wish to enter a new and dynamic field (SRO). 
This post could lead to either fully research-driven or staff-scientist career pathways. 

Responsibilities include, but are not limited to: 

- Data analysis on a variety of fast-developing spatial omics technologies available at WEHI including 10x Visium, 10x Xenium, BGI STOmics, and Vizgen MERSCOPE. 
- Leveraging and integrating the analysis of spatial omics data from different platforms and with other omics data types (e.g., single-cell RNA-sequencing). 
- Collaborative analyses with wet-lab and clinical researchers. 
- Communicating analysis results and methodologies to technical and non-technical researchers. 
- Developing statistical and computational methods to enable these analyses. 
- Benchmarking of technologies and analysis methods to develop technology recommendations and best-practice data analysis workflows. 

Selection Criteria 
- PhD or equivalent in statistics/bioinformatics (or other relevant disciplines) with a strong interest in biological research. Research experience is advantageous. 
- Demonstratable knowledge and experience in a data analysis programming language (e.g., R, Python). 
- Ability to work independently and in a multi-disciplinary team. 
- Effective time management skills and ability to work on several projects in parallel. 
- Strong communication skills, written and oral, and an ability to communicate technical concepts to non-technical researchers. 
- A basic understanding of molecular biology and sequencing is highly desirable. 

This position is available for an initial period of 2 years in a full-time or near-full-time capacity. Salary is RO/SRO ($105,555-$125,339).

Job website: http://wehi.wd3.myworkdayjobs.com/en-US/WEHI/details/Bioinformatics-Research-Officer---Senior-Research-Officer_JR1916-3

Contact name: Peter Hickey

Contact email: hickey@wehi.edu.au