Research Officer, Computational Cancer Biology and Bioinformatics @ Melbourne

Position title: Research Officer, Computational Cancer Biology and Bioinformatics
Employer: Walter and Eliza Hall Institute of Medical Research

Closing date: Feb 1, 2021, 5:00pm

Brief position description:

An exciting new opportunity exists for a talented bioinformatics researcher to join the Davis Laboratory in the Bioinformatics Division at WEHI. 

The position will involve the development of new research methods in computational cancer biology involving the analysis of data from newly emerging technologies such as spatial transcriptomics and spatial proteomics. This position will present ample opportunities to participate in active collaborative research projects across Australia. The successful candidate will also have the opportunity to supervise post-graduate students and participate in the development of new research directions and projects.

The Davis Laboratory applies mathematical, statistical, and computational approaches to drive new cancer discoveries using a combination of large, heterogeneous datasets and targeted experimental data. A major focus of their work is reconstruction of mechanisms of regulation involved in cancer progression and metastasis as well as response to therapy and development of resistance. This is a highly multi-disciplinary research laboratory, and post-doctoral staff and students come from a variety of backgrounds, including statistics, mathematical biology, bioengineering, computer science and genetics.

A position description is available here.

Selection Criteria

Personal qualities

  • Excellent attention to detail, ensuring that data analysis, new methods and software implementations are of high-quality and accessible to other researchers

  • Highly collaborative with excellent communication skills and the ability to work constructively in a team environment

  • Ability to manage time effectively and be reliable and approachable

  • A passion to work at the intersection of computational research, bioinformatics and biomedical research

Knowledge and skills

  • A PhD in a relevant discipline such as bioinformatics, computational biology, computer science, statistics, mathematics, physics or biology with strong and demonstrated computational skills

  • Strong programming and data analysis skills, and a knowledge of the R and/or python programming language(s)

  • Experience applying analytical and computational skills to large, complex data, including gene expression, proteomics and clinical data

  • Excellent time management, writing and communication skills.

  • Knowledge or understanding of cancer biology would be highly regarded

  • An excellent academic record and achievements

  • Demonstrated ability and potential for excellence and productivity in research

  • Research experience that has resulted in publications, conference papers or reports, or an excellent PhD thesis.

Terms of appointment

The position will be for 2 years in a full-time capacity. Salary is Academic Level A6-A8 ($90,053-$96,661). Up to 17% superannuation and very attractive salary packaging options are available.

How to apply

General enquiries can be directed to Melissa Davis; davis.m@wehi.edu.au

Please email your application including cover letter, CV and a letter addressing the key selection criteria in pdf format to jobapplications@wehi.edu.au, quoting the reference WEHIDAMD211220 

Job website: www.wehi.edu.au/research-officer-computational-cancer-biology-and-bioinformatics

Contact name: Melissa Davis

Contact email: davis.m@wehi.edu.au

Computational CRISPR Genomics - Bioinformatician @ Melbourne

Position title: Computational CRISPR Genomics - Bioinformatician

Employer: Walter and Eliza Hall Institute of Medical Research

Closing date: Feb 1, 2021

Brief position description: An exciting new opportunity exists for a talented bioinformatics research officer to work on computational CRISPR genomics and develop a key role for computational research in CRISPR activities.

The role will be joint between the laboratories of Prof Tony Papenfuss in the Bioinformatics division and A/Prof Marco Herold in the Blood Cells and Blood Cancers division. The successful candidate will work in close collaborations with bench scientists, contribute to the design of CRISPR experiments, analyse genomic and transcriptomic data, and develop new bioinformatics methods related to CRISPR.

The Papenfuss Laboratory applies mathematical, statistical, and computational approaches to drive new cancer discoveries using large and complex omics datasets. A major focus of their work is cancer evolution, which is critical in understanding how tumours metastasise and develop resistance to therapies. They have particular interests in developing methods for detecting and understanding genomic rearrangements and for applying mathematical modelling and machine learning to make sense of big data.

The Herold Laboratory aims to identify novel genes involved in the development of normal and malignant haematopoiesis. They are using in vivo CRISPR approaches to systematically identify new candidate genes, with the ultimate goal of using these targets as novel anti-cancer therapies. They are also developing new CRISPR models and methodologies (e.g. CRISPR activation or Base Editing) to resemble human disease more accurately and are implementing CRISPR as a diagnostic tool to ultimately use it for detection of infectious disease or malignant cells.

Job website: www.wehi.edu.au/research-officer-computational-crispr-genomics

Contact name: Tony Papenfuss

Contact email: papenfuss@wehi.edu.au

Post doc positions (2) @ Leipzig, Germany

Position title: Post doc positions (2) in Leipzig, Germany

Employer: Ulisses Nunes da Rocha, PhD, Helmholtz Young Investigator, Microbial Data Science and team leader, Department of Environmental Microbiology, Helmholtz Centre for Environmental Research

Closing date: open now from December 2020

Brief position description: Ulisses Nunes da Rocha, PhD, Helmholtz Young Investigator at the Microbial Data Science and team leader in the Department of Environmental Microbiology at the Helmholtz Centre for Environmental Research is seeking two bioinformatics post-docs to work with the them.

Sitz der Gesellschaft/Registered Office: Leipzig

Registergericht/Registration Office: Amtsgericht Leipzig

Handelsregister Nr./Trade Register Nr.: B 4703

Vorsitzender des Aufsichtsrats/Chairman of the Supervisory Board: MinDirig Wilfried Kraus

Wissenschaftlicher Geschäftsführer/Scientific Managing Director:

Prof. Dr. Georg Teutsch

Administrative Geschäftsführerin/Administrative Managing Director:

Prof. Dr. Heike Graßmann

Job website: http://www.ufz.de/index.php?en=43659

Contact name: Ulisses Nunes da Rocha

Contact email: ulisses.rocha@ufz.de

Research Officer- Computational Systems Biology @ Sydney

Position title: Research Officer- Computational Systems Biology @ Sydney

Employer:

Closing date: 21st December 2020

Brief position description: The Computational Systems Biology (CSB) lab at CMRI is welcoming applications for a Research Officer to conduct research in the broad area of systems stem cell biology and single-cell multi-omics. Our research focuses on the acquisition of stem cell identity and cell fate decisions during differentiation and together the two CMRI labs have established high-throughput experimental techniques such as single-cell omics and computational expertise in multi-omics data analysis.

The CSB lab collaborates closely with other groups and units at CMRI (e.g. Embryology) and also a team of bioinformaticians from the School of Mathematics and Statistics, and systems biologists from Charles Perkins Centre (CPC), at the University of Sydney. The appointee will have ample opportunity to collaborate with bioinformaticians within CMRI and from the School of Mathematics and Statistics, and systems biologists from Charles Perkins Centre (CPC) at the University of Sydney.

Duration: 3-year fixed term (full time).

Salary: $88,499 – $94,998 + Superannuation + Annual Leave Loading + Salary Packaging

About the role

This position will help you building a collaboration network across multiple institutes and a track record that enables you to apply for collaborative research funding and independent research fellowship. Specific roles include (but not limited to) the following:

Lead and carry out research projects in the broad area of systems biology, stem cells biology, and single-cell multi-omics.
Prepare and publish work on scientific journals and present scientific results in national/international conferences.
Develop and co-supervise research projects for undergraduate and graduate research students.
Assist in the recruitment of research students and continuously working towards attracting new funding.
Build collaboration with different labs in CMRI and across multiple institutes/universities at Sydney (e.g. CPC and School of Mathematics and Statistics) and beyond.
About you

We are look for someone with the follow characteristics and research experience.

• A PhD in an appropriate area such as (but not limited to) computational and systems biology, bioinformatics, computer science, statistics or another closely related scientific discipline.

• Proven research ability, and evidence of self-motivation and research potential

• Demonstrated experience with omics, bioinformatics, systems biology and molecular biology

• Demonstrated experience with machine learning, deep learning and data analytics

• Proven excellence in written and oral communications, interacting with a variety of researchers and stakeholders

• Proven commitment to producing high quality work and a demonstrated track record of high-quality publications

• Demonstrated excellence in research within bioinformatics or computational systems biology through published research in refereed journals

• Proven ability to write and contribute to bioinformatic, computational, statistical, or mathematical research papers

• Knowledge of stem cells and development

Computational Systems Biology group

CSB lab (https://pyanglab.github.io) combines computational ('dry') and experimental (‘wet’) expertise to understand stem cell systems. The lab resides in CMRI, Westmead, while also holding office space at both School of Mathematics and Statistics and Charles Perkins Centre, USyd, which enable ample collaboration with statisticians and bioinformaticians; computational and systems biologists; and molecular and developmental biologists.

Current focus of the lab is on transcriptional regulation in stem cells (Yang et al. Molecular Cell, 2017; Kim…Yang, Nucleic Acid Research, 2020); bulk and single-cell multi-omics analysis (Yang et al, Cell Systems, 2019; Kim…Yang, Bioinformatics, 2020); and machine learning application in systems biology (Cao…Yang, Nature Machine Intelligence, 2020). The overarching goal of the lab is to develop computational methods for characterising stem cell systems and harnessing them for tissue regeneration.

You will be provided with a competitive remuneration package in accordance with qualifications and experience. Additional benefits include the provision of a Public Benevolent Institution salary packaging scheme and participation in an employer-contributed superannuation fund.

Applications should include a cover letter (citing PV2038), curriculum vitae and contact details (phone/email) of three professional referees and be forwarded to recruitment@cmri.org.au

Closing date for applications is 21st December 2020.

Please direct enquiries regarding the position to Dr Pengyi Yang, NHMRC Investigator, pengyi.yang@sydney.edu.au.

Job website:

Contact name: Pengyi Yang

Contact email: pengyi.yang@sydney.edu.au

Bioinformatics Research Officer/Research Assistant @ Melbourne

Position title: Bioinformatics Research Officer/Research Assistant

Employer: WEHI

Closing date: 18 December 2020

Brief position description: An opportunity exists for a talented and motivated Research Officer and/or Research Assistant to work with A/Prof Matt Ritchie in the Epigenetics and Development Division at WEHI.

The Ritchie Laboratory uses statistical methodologies to provide new insights into the genetic basis of health and disease. They develop specialised analysis methods for large and complex genomics datasets (e.g. bulk and single cell RNA-seq, long-read RNA-seq and long-read methylation profiling) implemented in open-source software through the Bioconductor project. They collaborate with research groups throughout the Institute to uncover changes in gene regulation that occur during development and in the context of diseases such as cancer.

The successful candidate for a Research Officer role will have a PhD in Statistics, Mathematics, Computer Science, Bioinformatics or Computational Biology, strong computational skills, and experience applying these skills in the analysis of large and complex datasets.

The successful candidate for a Research Assistant role will have an Honour’s or Master’s degree in Mathematics, Statistics, Computer Science, Bioinformatics or Computational Biology.

Job website: http://www.wehi.edu.au/bioinformatics-research-officerresearch-assistant-parental-leave-cover

Contact name: Matt Ritchie

Contact email: mritchie@wehi.edu.au

Research Officer in Marine Genomics @ Perth, WA

Position title: Research Officer in Marine Genomics

Employer: Minderoo Foundation, Perth, WA

Closing date: 18 Dec 2020

Brief position description: The Minderoo OceanOmics program is seeking a dynamic, motivated Research Officer with experience in marine genomics to join their team. In this role, you will participate in the conception and execution of a variety of experimental procedures focused on using marine cell-free and cell-bound DNA in combination with next-generation sequencing to understand and advance marine ecology.

Job website: http://www.seek.com.au/job/50983232

Contact name: Minderoo Foundation

Contact email:

Australian BioCommons Senior Bioinformatics Officer @ NSW

Position title: Australian BioCommons Senior Bioinformatics Officer

Employer: University of Sydney

Closing date: 11:30pm, Thursday 3 December 2020

Brief position description: In this role as an Australian BioCommons Senior Bioinformatics Officer, you will contribute to the BioCommons Bring Your Own Data (BYOD) platform project, delivering a suite of software and workflow development and deployment activities that enables highly accessible, available, y scalable analysis and data sharing capabilities for the benefit of life science researchers nationally.

You will focus on developing and delivering a Command Line Interface (CLI)-focussed BYOD platform. The CLI-focussed platform will provide a scalable and flexible set of open programmatic resources to create, access and exchange workflows, tools and training across national, institutional, and commercial compute infrastructures.

About you

The University values courage and creativity; openness and engagement; inclusion and diversity; and respect and integrity. As such, we see the importance of recruiting talent aligned to these values and are looking for an Australian BioCommons Senior Bioinformatics Officer who demonstrates:

experience in working in a Linux/UNIX using scientific computing languages such as Python, Perl, R, shell scripting and/or other relevant languages
experience working with HPC clusters and job schedulers e.g. PBS, SLURM
postgraduate qualifications or an equivalent combination of experience and/or training in a relevant field
Knowledge and experience with analysing Next Generation Sequencing (including whole genome sequencing or long read sequencing) and other ‘omics’ data
experience developing and deploying pipelines using software containers and workflow languages
familiarity with code performance optimisation considerations and approaches
project management skills and can manage competing priorities to required timelines
experience in an academic environment
excellent written and verbal communication skills.

About us

The Sydney Informatics Hub (SIH) is a University Core Research Facility serving academics and researchers across all faculties through the provision of comprehensive research data services. As a Core Research Facility, Sydney Informatics Hub aims to provide comprehensive data services to the University’s research community. Initially established to provide software engineering and data analytics services to researchers, the Hub now also offers services, training and support for Research Computing (leveraging the University’s High Performance Computing cluster, Artemis, and other emerging digital infrastructure), Statistical Consulting, and Research Data Strategy and consulting.

The Australian BioCommons is a new research infrastructure sponsored by Bioplatforms Australia. The Australian BioCommons aims to enhance the productivity, capability and capacity of Australian research biologists and research bioinformaticians.

https://www.sydney.edu.au/research/facilities/sydney-informatics-hub.html

Since our inception 160 years ago, the University of Sydney has led to improve the world around us. We believe in education for all and that effective leadership makes lives better. These same values are reflected in our approach to diversity and inclusion and underpin our long-term strategy for growth. We’re Australias first university and have an outstanding global reputation for academic and research excellence. Across our campuses, we employ over 8,100 academic and non-academic staff who support over 73,000 students.

We are undergoing significant transformative change which brings opportunity for innovation, progressive thinking, breaking with convention, challenging the status quo, and improving the world around us.

How to apply

For more information on the position and University, please view the position description available from the job’s listing on the University of Sydney careers website.

All applications must be submitted via the University of Sydney careers website. Visit https://sydney.edu.au/about-us/careers-at-sydney.html and search by the reference number 1114/0920F-1 to apply.

Please note: Visa sponsorship is not available for this position

Closing date: 11:30pm, Thursday 3 December 2020

The University of Sydney is committed to diversity and social inclusion. Applications from people of culturally and linguistically diverse backgrounds; equity target groups including women, people with disabilities, people who identify as LGBTIQ; and people of Aboriginal and Torres Strait Islander descent, are encouraged.

© The University of Sydney

Job website: http://www.seek.com.au/job/50982932

Contact name: Tooba Fida

Contact email: tooba.fida@sydney.edu.au

Bioinformatician in Computational Functional Genomics @ NSW

Position title: Bioinformatician in Computational Functional Genomics

Employer: Children's Medical Research Institute

Closing date: 11th December 2020

Brief position description: We are seeking a qualified Bioinformatician / Data Scientist to join the Functional Genomics program with a focus on proteomics. This role will involve supporting researchers from the CMRI and collaborating institutions in the analysis of proteomics data of rare genetic diseases, cancers and disease modelling.

Job website: http://www.seek.com.au/job/50951796?_ga=2.42768813.929932421.1605470582-1921069189.1595562168

Contact name: Paulina Baranowski

Contact email: pbaranowski@cmri.org.au

Research Officer – Computational Biology & Bioinformatics @ Victoria

Position title: Research Officer – Computational Biology & Bioinformatics

Employer: oNKo-innate Pty Ltd

Closing date: Monday 2 November 2020, 11:55pm AEDT

Brief position description: The Computational Biology & Bioinformatics team at oNKo-innate work with large public data resources and proprietary in-house data obtained through our Screening, Biologics, and Cell Therapies platforms. The Research Officer performs a range of activities to support our Target Discovery teams to develop machine learning models and pipelines that guide target prioritisation and aid in the development of next-generation immunotherapies. These include analysis of sequencing data, bash scripting or developing pipelines for high-performance compute clusters, and/or with Amazon Web Services or other cloud-based platforms, and application of methods that may be relevant to machine learning pipelines.

The successful candidate will have experience with python and appropriate scientific libraries, an understanding of molecular biology, cancer biology, or tumour immunology, and thrive in a fast-paced environment and be able to adapt and respond to arising challenges. This is a dynamic role in a goal-oriented and collaborative environment with an opportunity for further growth.

Job website: http://careers.pageuppeople.com/513/cw/en/job/611351/research-officer-computational-biology-bioinformatics

Contact name: Joe Cursons

Contact email: joe@onko-innate.com

(Sent via Australian Bioinformatics And Computational Biology Society)

Postdoctoral Researcher @ Queensland

Position title: Postdoctoral Researcher

Employer: The university of Queensland

Closing date: 12 Nov 2020 (11:00 PM) E. Australia Standard Time

Brief position description: The primary purpose of this role is to apply cutting edge computational approaches to understand the molecular underpinnings of cellular identity and ageing. The Postdoctoral Research Fellow will leverage bulk and single cell multiomic data sets (RNA-seq paired with ATAC-seq) to characterize transcription factor network changes driving reprogramming processes and cellular ageing. This position joins the multidisciplinary Nefzger group made up of wet-lab and computational biologists and will collaborate closely with the Nguyen group, IMB where spatial transcriptomics data sets from young and aged organs will be analysed.

Job website: http://search.jobs.uq.edu.au/caw/en/job/511582/postdoctoral-research-fellow

Contact name: Christian Nefzger

Contact email: c.nefzger@imb.uq.edu.au