RESEARCH OFFICER/POSTDOCTORAL FELLOW IN BIOINFORMATICS/COMPUTATIONAL BIOLOGY

Employer: South Australian Health & Medical Research Institute (SAHMRI)

Closing date: This position will remain open until a suitable candidate is identified.

Brief position description: The Lynn EMBL Australia Group at the South Australian Health and Medical Research Institute (SAHMRI) in Adelaide, Australia is now seeking applications for a bioinformatics/computational biology researcher to work on a variety of projects in the cancer systems biology and systems immunology areas. Prior experience in at least some of the following areas is essential: analysis of next generation sequencing (NGS) data; network and pathway biology; cancer systems biology; machine learning methods and experience in biomarker discovery and validation. Active collaboration and the ability to manage multiple different projects simultaneously is essential. An initial 2 year full-time contract is available, potentially renewable.

The successful candidate will work as part of a multi-disciplinary team that is equally divided between computational and experimental systems biology. The group is headed by Prof. David Lynn, who also heads the SAHMRI Computational and Systems Biology Program, one of 16 research programs at the institute. The group is currently funded by EMBL Australia Group Leader funding, The NHMRC, Cancer Australia, as well as several smaller grants and consists of five senior postdoctoral researchers, two research officers as well as PhD and honours students, who employ in vitro and in vivo experimental and clinical models coupled with systems biology approaches to investigate cancer and the immune system. On the bioinformatics side, the group leads the development of a wide range of bioinformatics applications including InnateDB.com, an internationally recognised systems biology platform. David has also led the computational biology aspects of €12 million European Commission funded cancer systems biology project.

Please see https://www.sahmriresearch.org/human-resources/careers/218 for a position description and to apply.
The position will remain open until a suitable candidate is identified.

Job website: http://www.sahmriresearch.org/human-resources/careers/218

Contact name: David Lynn

Contact email: david.lynn@sahmri.com



Research Officer/Senior Research Officer

Employer: The Walter and Eliza Hall Institute

Closing date: 10/04/2019

Brief position description: This position will lead research projects to identify regulatory mechanisms implicated in cancer plasticity and progression. The successful applicant will have strong analytical skills and experience in the analysis of complex, high-dimensional data, with an interest in cancer. This position also presents opportunities to participate in national and international collaborations, participate in projects with industry partners, and gain experience supervising research students.

Job website: http://www.wehi.edu.au/research-officer-senior-research-officer-davis-laboratory

Contact name: Melissa Davis

Contact email: davis.m@wehi.edu.au

Research Officer / Senior Research Officer - Bioinformatics/ Computational Biology

Employer: Garvan Institute of Medical Research

Closing date: This role will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.

Brief position description: The Opportunity
We are seeking a Research Officer / Senior Research Officer to investigate the earliest steps in cancer initiation and evolution, integrating bioinformatic and population genetic methods. 

Reporting to Professor David Thomas, Laboratory Head – Genomic Cancer Medicine, the key responsibilities include:
• Planning and executing research
• Developing methods to extract quantitative, ultra-low frequency variation from sequence data derived from tumor and blood samples.
• Analysing ultra-low frequency clonal variation in in vitro clonal evolution under selective pressures;
• Applying these methods to quantitate clonal neoplastic events in an extremely cancer-prone population with Li-Fraumeni syndrome; and
• Analysing the whole genomes of more than 20 tumors arising in a cancer-prone family, aiming to identify the common pathways resulting in the formation of tumors in a defined genetic context.

The role will be offered full-time for 2 years in the first instance.

About You
The successful candidate will possess the following key skills and qualifications:
• A PhD in bioinformatics or computational biology, or equivalent experience in a related field.
• Proficiency with genotyping of human samples using massively parallel sequencing technology.
• Ability to manage and process large datasets in a POSIX environment.
• Fluency in at least one scripting language.
• Excellent communication skills and strong in team work and collaborative research
• Ability to conceptualise and execute a research plan to investigate an open-ended question, with minimal supervision.
• A proven track record e.g. publications, grants, software/tool development
• Familiarity with the ethical issues and guidelines relating to the use of human tissue and clinical data for research
• Statistical expertise and experience with the R programming language and key libraries is highly desirable.
• Knowledge of cancer biology and evolution is highly desirable.

Job website: http://garvan.applynow.net.au/jobs/GC201934

Contact name: Human Resources

Contact email: <not provided>



Junior Bioinformatics Developer

Employer: Longas

Closing date: 18/3/2019

Brief position description: We’re a biotech startup launched by UTS with Australia-based venture backing. We’re developing advanced DNA sequencing methods that should make a huge impact in the molecular biology research and diagnostics space. We’re looking for an enthusiastic junior developer to join us.

We have a maturing data processing pipeline that includes several existing bioinformatics applications as well as a some bespoke tools developed in house. We’re looking for someone to help us design, implement and optimise sequence analysis algorithms for de novo human and microbial genome assembly by creating and using long read sequencing data.

We’re a small team which means that we’re regularly touching the code at multiple places across the stack including: algorithm development, testing, data management, ops / deployment and QA. Our main algorithm is written primarily in Python and C++ but we support that code using several existing bioinformatics tools deployed on Linux, Amazon Web Services, Nextflow, Ansible, git and a few of the toys from Hashicorp.

We’re an agile team and we’re committed to continuously improving our code, our processes and of course, ourselves. We offer a friendly working environment with ability to spend some time working remotely.

Job website:

Contact name: Aaron Darling

Contact email: aaron.darling@longastech.com



BIOINFORMATICS ENGAGEMENT OFFICER (RE-ADVERTISED)

Employer: Melbourne Bioinformatics

Closing date: 27 Mar 2019 11:55 PM AUS Eastern Daylight Time

Brief position description: Job no: 0047174
Work type: Fixed Term
Location: Parkville
Division/Faculty: Faculty of Medicine, Dentistry and Health Sciences
Salary: $98,775 - $117,290 (NH & MRC Senior Research Officer, Level B)
Role & Superannuation rate: Academic - 17% superannuation

This is a full-time fixed term position for three years.

The appointment will be made at either NHMRC Research Officer Level A - $87,415 - $93,830 p.a. or NHMRC Research Officer Level B - $98,775 - $117,290 p.a. (plus 17% superannuation), subject to qualifications and experience. 

Reporting to the Director of the Australian Bioinformatics Commons within Melbourne Bioinformatics, and funded by Bioplatforms Australia, this new position will be directly involved in coordinating and supporting high profile research collaborations across Australia that utilise various Bioinformatic analyses. Bioplatforms Australia manages a national network of accessible genomics, proteomics and metabolomics facilities for Australia.

Bioplatforms Australia also catalyses nationally collaborative initiatives to develop large scale datasets through development of data generation and analysis workflows as well as capacity building resources to help address challenges of significance to Australia. Bioplatforms Australia develops and manages these large and complex collaborations in partnership with the research community across the breadth of the life science sector: http://www.bioplatforms.com/projects/

The nationally inclusive nature of these Framework initiatives (i.e. many and varied consortium participants) in addition to an approach that requires the research community to contribute new and existing resources (i.e. samples, data, metadata, analysis pipelines, bioinformatics analysis effort) means dedicated, active and effective engagement and coordination is critical to success.

The bioinformatics requirements for this portfolio of national collaborations requires dedicated engagement, coordination and management. Working with bioinformaticians, biologists, e-Research providers, data and project managers from the Bioplatforms network and wider research community you will coordinate the bioinformatics requirements for these Framework initiatives.

This is a re-advertised position. Previous applicants need not re-apply.

Job website: http://jobs.unimelb.edu.au/caw/en/job/898314/bioinformatics-engagement-officer-readvertised

Contact name: Andrew Lonie

Contact email: alonie@unimelb.edu.au

Research Officer - Bioinformatics - The Australian National University

Job no: 528296
Work type: Continuing (Contingent Funded)
Location: Canberra / ACT
Categories: Professional
Classification: ANU Officer 5/6 (Research)
Salary package: $70,078 - $82,651 per annum plus 17% superannuation 
Term: Continuing, Contingent Funded 

The ANU College of Science (CoS) comprises: the Research School of Astronomy and Astrophysics, the Research School of Biology, the Research School of Chemistry, the Research School of Earth Science, the Fenner School of Environment and Society, the Mathematical Sciences Institute, the Research School of Physics and Engineering, and the Centre for the Public Awareness of Science.  Staff and students within the ANU College of Science conduct research and delivers a research-led education program that encompasses the entire breadth of the sciences, supported by extensive international networks and by world-class facilities.  The College has a strong tradition of research excellence that has fostered distinguished Nobel Laureates and Kyoto Prize winners and that trains scientific leaders in disciplines in which the ANU is consistently ranked in the top twenty in the world.

We seek applicants for a Research Officer position in genomic bioinformatics to support projects on evolutionary genetics of Australian vertebrates. These ARC-supported projects include landscape genetics in small mammals using SNP data, genome evolution in rock wallabies, and molecular evolution and diversity in tropical reptiles. The appointee will work under the direction of Craig Moritz, and engage with others in his research group and other labs in RSB to:

  • Understand bioinformatics requirements for downstream analyses in evolutionary genomics;

  • Develop, document and provide training in the use of bioinformatics pipelines; and

  • Prepare and assess quality of datasets from SNP (ddRAD) screening, target sequence capture, or whole genome resequencing.

The successful applicant will have:

  • A higher degree, or equivalent experience, relevant to these tasks;

  • Substantial expertise in handling genome (re)sequencing data and/or genome assembly, including scripting pipelines in Python or PERL; and

  • Strong organizational skills and ability to multitask and complete projects in a timely fashion

  • Good team work and communication skills.

  • Understanding of principles of molecular evolution or population genetics would be an advantage.

This position is continuing, contingent on external funding (CCF), the initial funding period is one (1) years with the possibility of extension pending funding availability.

For more information, please contact Professor Craig Moritz on craig.moritz@anu.edu.au

ANU values diversity and inclusion and is committed to providing equal employment opportunities to those of all backgrounds and identities. For more information about staff equity at ANU, visit https://services.anu.edu.au/human-resources/respect-inclusion

Application Information

http://jobs.anu.edu.au/cw/en/job/528296/research-officer-bioinformatics

In order to apply for this role please make sure that you upload the following documents:

  • A statement addressing the selection criteria.

  • A current curriculum vitae (CV) which includes the names and contact details of at least three referees (preferably including a current or previous supervisor). If your CV does not include referees you can complete these online when prompted in the application form.

  • Other documents, if required.

Applications which do not address the selection criteria may not be considered for the position.

Please note: The successful applicant must have rights to live and work in this country. 


Applications close: 10 Mar 2019 11:55:00 PM AUS Eastern Daylight Time

Technical Officer (Bioinformatics), Hong Kong

Position title: Technical Officer (Bioinformatics)

Employer: The University of Hong Kong

Closing date: 20 February 2019

Brief position description: The School of Biomedical Sciences is looking for a technical officer who can assist in research activities in bioinformatics and provide technical support to the School including the transfer and back-up of computer data, managing large data compression, and the set-up and maintenance of computer servers.

Applicants should possess a Bachelor's degree in Computer Engineering, Software Engineering, Computer Science or a related discipline, with at least 2 years’ work experience in the Unix operating system, scripting language (e.g. shell, perl, or python) and web technology (e.g. HTML5, CSS, PHP, and SQL). Those with sound knowledge in commercial cloud computing platforms would be highly preferred. Applicants should also be highly motivated, and able to work independently and as a team in a multi-disciplinary laboratory environment.

A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits. The position is to commence as soon as possible, on a two-year fixed-term basis with contract-end gratuity and University contribution to a retirement benefits scheme, totalling up to 10% of basic salary, with the possibility of renewal.

Expression of interest can be directed to Dr Joshua Ho (jwkho@hku.hk). Full application should be made online (click 'Apply now' on http://jobs.hku.hk/cw/en/job/493856/technical-officer). Review of applications will start as soon as possible and continue until February 20, 2019, or until the post is filled, whichever is earlier.

Job website: http://jobs.hku.hk/cw/en/job/493856/technical-officer

Contact name: Joshua Ho

Contact email: jwkho@hku.hk

Postdoc in machine learning applied to gene regulation, France

Position title: Postdoc in machine learning applied to gene regulation

Employer: CNRS

Closing date: 1/3/2019

Brief position description: A two-year postdoctoral position is available in the machine learning and gene regulation group directed by William Ritchie at the Institut de Génétique Humaine in Montpellier, South of France. The IGH is a world leader in the field of gene regulation, with state-of-the art facilities and teams of international renown.

Our group uses machine learning approaches to integrate omics data to understand normal biology and disease. We have a strong background in applying novel algorithmic approaches to better understand mechanisms of gene expression and RNA processing (Middleton et al., Genome Biology, 2017; Wong et al., Nature Comms, 2017; Wong et al., Cell, 2013).

We have currently generated a wealth of transcriptomic data (mRNA-seq, ONT long-read seq) and epigenetic data to dissect the epithelial to mesenchymal transition underlying tumor progression and metastasis. We will integrate this data as well as explore long range interactions that may regulate RNA processing through direct contact with enhancers. 

We are therefore looking for very motivated, hard-working and creative candidates with strong background in computer science or statistics to explore RNA regulation through epigenetic and long range interactions. Previous expertise in RNA processing and/or epigenetics will be positively evaluated.

Job website: http://www.igh.cnrs.fr/en/about-igh/job-opportunities/320-postdoc-machine-learning-applied-to-transcriptomic-data-in-a-model-of-metastasis-hf

Contact name: william ritchie

Contact email: william.ritchie@igh.cnrs.fr



Research Officer – Bioinformatics of Speech Disorders, Melbourne

Position title: Research Officer – Bioinformatics of Speech Disorders

Employer: Walter and Eliza Hall Institute of Medical Research

Closing date: 5:00pm, Friday 1st March 2019

Brief position description: An opportunity exists for a Research Officer specialising in the genetics of speech disorders to join the Bahlo laboratory. The successful candidate will join an international collaboration between speech pathologists, geneticists, imaging and bioinformatics experts.

About the position:
The appointee will undertake bioinformatics analyses of genetic data generated for family and cohort studies in speech disorders, interacting with genetic, clinical and imaging experts involved in understanding the speech phenotypes in the patients. The data will be primarily next generation sequencing data from whole-exome, whole-genome sequencing or targeted sequencing of cohort and family-based studies. The research officer will oversee several exciting studies, analysing data, analysing and managing the research outcomes from these projects. The research officer will also integrate with other work in the Bahlo laboratory to apply novel methods for prioritisation of putative speech disorder candidate genes, which can be assessed in large national and international cohorts. The work is highly likely to lead to high-impact publications with the expectation of presentations at national and international conferences. The research officer will use advanced bioinformatics tools developed at the WEHI and elsewhere and will have access to high quality computing facilities.

Selection Criteria:
Applicants with a PhD in a relevant discipline are welcome to apply. Relevant disciplines include computer science, mathematics, statistics, computational biology or genetics. Applicants need to have extensive experience in the analysis of next generation sequencing data and a good understanding of genetics with a proven research track record of publications. Experience in speech disorder genetic research is desirable, but not essential. The position requires high-level project-management skills, strong programming and data analysis skills and, in particular strong communication skills to ensure excellent communication as a key person working between the two laboratories.

Terms of appointment: 
The positions will be for 2 years in the first instance. Salary is dependent upon qualifications and experience. Up to 17% superannuation and attractive salary packaging options are available.

Job website: http://www.wehi.edu.au/research-officer-%E2%80%93-bioinformatics-speech-disorders

Contact name: Melanie Bahlo

Contact email: bahlo@wehi.edu.au